links to hair growth?
a study done on three different animals, a rabbit, guinea-pig
and mouse with different types of topical Zinc formulations,
one of the effects noticed was increased hair growth. In the
variations in response to topical application of selected
zinc compounds animals; Zinc oxide, zinc sulfate
and zinc pyrithione were found to cause increased hair growth.
interesting study that showed the possible way that Zinc Oxide
may stimulate hair growth was one a study titled: "Topical
zinc oxide treatment increases endogenous gene expression
of insulin-like growth factor-1 in granulation tissue from
porcine wounds. In this study done on pigs it was
shown that Topical Zinc Oxide increased IGF-1 concentrations
is very interesting and good news since it has been theorized
in a published paper that increasing IGF levels may stimulate
hair growth. In the paper titled Insulin-like
growth factor 1 and hair growth it was suggested based
on research that IGF-1 may be able to stimulate the proliferation
of hair follicle cells through cellular signaling pathways
of its receptors. The authors looked at existing research
that had shown that local infusion of IGF-1 into sheep has
been reported to be capable of stimulating protein synthesis
in the skin and may also increase the production of wool keratin.
Also recently, transgenic mice overexpressing IGF-1 in the
skin have been shown to have earlier hair follicle development
than controls. The authors went on to suggest that studies
should be done on IGF-1 and hair growth.
in conclusion, separate studies have shown that Zinc Oxide
increases wound healing, increases IGF-1 and that other forms
of zinc reduce 5 alpha-reductase activity. So it definitely
appears that zinc oxide is a useful addition to any hair growth
to use it?
original idea to use Zinc oxide for hair loss came out of
a patent where Zinc oxide and Boric acid were combined and
applied as a hair growth stimulant. The patent is titled:
comprising starch, a compound comprising boron, a compound
comprising zinc, and water, and a method of using same to
encourage hair growth.
patent describes the method used to create the Zinc Oxide
mixture which has been tried by many people in their kitchens.
Hair loss sufferers have been experimenting with creating
their own formulations and variations of the mixture and substituting
Ascorbic Acid since Boric Acid is not recommended. Boric Acid
ingestion is considered harmful and may be fatal. It can also
be harmful by inhalation, is an irritant, and may cause congenital
malformation in the fetus. Therefore it is not recommended
to use Boric Acid.
need for cooking up the ingredients and the cost of buying
them have put a lot of people off using it. However it may
not be necessary to go to such lengths. The original formulation
comes from Hokkaido, Japan where it was used as a wound healing
preparation. The good news is that there was a study done
by the Japanese to determine if the same results could be
obtained without Boric Acid and the results were that it could.
In a study Clinical
studies on zinc oxide ointment replacing boric acid and zinc
oxide ointment, it was shown that the zinc oxide ointment
without boric acid had the same effect on wound healing as
the boric acid and zinc oxide ointment.
study suggests that Zinc Oxide on its own is sufficient and
there is no need to create a special mixture with boric acid.
to get it?
are several creams on the market that contain zinc oxide,
zinc oxide is used is various diaper rash and skin creams.
The formulation that we recommend and that is used by many
people is the Zinc Cream made by Margarite. The cream is designed
for application to the face and is flesh tone tinted. It contains
30% zinc oxide, sulphur and is in a greaseless base. If you
use this cream you will not need to add anything into it as
its already formulated for application to the skin.
often should you use it?
is no specific amount of times to use zinc oxide. Since it
is a cream its better applied at night and washed out in the
morning. Ideally it should be used 3-5 times per week. If
you are using other topicals its better to apply them first
and then apply the zinc oxide afterwards. It
is recommended that if you are using zinc that you also use
a copper-based product like Tricomin or Folligen. The reason
for this is that copper and zinc compete for absorption so
they need to be kept in balance. One way to do this is to
apply the zinc at night and the Tricomin in the morning.
safe is it?
is one of the least toxic of the trace elements. Oral zinc
supplements in large amounts (for example, 70 to 100 times
the recommended amounts) may cause diarrhea, abdominal cramps,
and vomiting usually occurring within 3 to 10 hours of the
ingestion of the supplements. The symptoms diminish within
a short period of time after the discontinuation of the supplements.
Topically, zinc oxide does not appear to be likely to cause
any overdose. In this study: Release
and absorption of zinc from zinc oxide and zinc sulfate in
open wounds, zinc oxide delivered zinc ions to wounds
over an extended period of time which resulted in constant
wound tissue zinc levels.
Oxide is a cheap addition to any hair loss regime with proven
benefits in wound healing and it very likely stimulates hair
growth in humans as it does in animals. Users can take advantage
of pre-made creams and do not have to rely on home made concoctions
to get the benefits of zinc oxide. We recommend adding zinc
oxide cream into a hair loss treatment regime for additional