Folligen products contain a high concentration of blue-colored
copper-peptide complexes designed to improve scalp and hair
follicle health and hair vitality
Folligen is a non-drug product that had its beginning as a skin
repair cream that was being tested in the Dermatology Department
at the University of California at San Francisco. After 41-year-old
woman with severe hair loss tried one of the skin repair creams
and regrew her lost hair in two and one-half months, the company
decided to offer the product as a hair treatment. Skin Biology,
the company responsible for the cream has introduced several
new products based on the same Copper peptide technology.
Folligen products were designed by Dr. Loren Pickart, an inventor
with over 150 patents on tissue regeneration and the original
founder of Procyte Corp.
Folligen's biological effect on hair is similar to other copper-peptide
products such as Tricomin which are skin repair products that
aid hair growth and scalp health.
Research on skin and hair follicle renewal indicates that optimal
regeneration is obtained only when there are multiple signals
for renewal. Folligen contains copper ion plus a mixture of
numerous different peptides fragments that are generated by
natural proteolytic enzymes (as happens after follicle or scalp
damage). This produces numerous copper-peptide complexes in
a more natural manner to assist the hair's natural regenerative
Folligen rebuilds the protective acid mantle of the scalp that
shampoos and conditioners remove. The acid mantle is the combination
of sebum (oils) and perspiration, on the skin's surface that
protects the skin and renders the skin less vulnerable to damage
and attack by environmental factors such as sun and wind and
less prone to dehydration. The mantle also has strong anti-oxidant
properties and is itself oxidized to protect the skin from oxidation.
Sebum is naturally white but air oxidation turns it black (this
is why "whitehead comedos" turn into "blackhead comedos"). Normal
skin and scalp pH is somewhat acid and in the range of 4.2.
to 5.6. It varies from one part of the body to another and,
in general, the pH of a man's skin is lower (more acid) than
that of a woman's. The acid mantle inhibits the growth of foreign
bacteria and fungi and the skin remains healthier, and has fewer
blemishes. Acne, allergies and other skin problems become more
severe when the skin become more alkaline. Folligen adjusts
the scalp pH into the acid range of optimal scalp health at
about pH 5.0.
Folligen also contains high levels of lipids such as squalane,
cetyl alcohol, glyceryl stearate and stearic acid that closely
resembles the fats of the acid mantle. Furthermore, Folligen
contains antioxidants such as allantoin, aloe, vitamin E and
retinol to aid the mantles protective anti-oxidant properties.
In this manner, Folligen improves scalp health and aids hair
growth. Folligen works well with Minoxidil or the Minoxidil
and Retinoic Acid combination.
may help on its own but the best results have when used in combination
with products like Rogaine. Folligen cream or lotion help soothe
irritated scalps and alleviates the itching and burning associated
with using harsh alcohol based products like Rogaine. Folligen
cream is designed for use on hairlines, a more-liquid Folligen
Lotion is used in areas of denser hair. There is also a Folligen
Solution Therapy Spray which can be sprayed as a fine mist into
the hair. Folligen Spray does however seem to irritate some
peoples scalp so if you have a sensitive skin its better to
use the cream or lotion rather than the spray.
skin of the mouse to the left was shaved, then treated in
three spots with Folligen. The result is a much more rapid
hair growth (the three circular patches of hair) in the
three spots treated with Folligen. While human hair growth
will not respond nearly as dramatically as in mice, skin
health and hair follicle function are closely interrelated.
New skin appears to arise from the hair follicle. As a person
ages, our hair follicles get smaller, producing thinner
hair shafts. The blood circulation system that supplies
nutrients and oxygen to the hair follicle send fewer blood
vessels to the hair follicle, thus inhibiting the vital
flow of nutrients to the hair follicle. Copper-peptide complexes
improve skin health and a more healthy skin increases the
blood vessel network to the hair follicles resulting in
larger follicles that grow hair faster with thicker hair
is a natural product so there are no side effects. Some people
using the spray do report having an itchy or burning sensation.
The cream and lotion are a bright green color so are not suited
to be used in the morning. They should be used at night at with
some pillow cover as the green color can rub off on pillow cases.
Folligen is easily washed off in the morning, but some people
with very light blonde hair do report having a greenish tinge
on their hair. If you have very light blonde hair you should
not use this product.
cream or lotion is best used in combination with product like
Rogaine which helps soothe the scalp if its irritated and provides
copper nutrients to the follicles. Folligen spray can be used
as an alternative to Rogaine for those people not wanting to
use a drug treatment.