TSCHEN: Was there any effect in these patients, any other methodological
effect, as far as decrease in the oiliness of the skin, decrease
in seborrhea or seborrheic dermatitis or acne? I know there
are differences, but were these questions asked to these patients,
if their acne was better or if their skin got drier?
DR. WALDSTRAICHER: Right; the question is whether we've asked
about sebum production, oiliness of skin or acne in our clinical
studies. We did a 6-week study looking at scalp-skin DHT levels,
and in those same patients, on 6 weeks of finasteride at multiple
doses, we also measured sebum output using sebatape, which is
an established method, and we did not see a significant suppression
of sebum output with finasteride.
We also have not observed any reports of acne worsening or improving
in either group different from placebo.