Dr Ken Washenik - Medical Director of the Aderans Research
conducted this revealing two hour interview with Dr.
Ken Washenik at the Aderans Research Institute's offices
in Beverly Hills, California in December 2002.
is the state of the Aderans Research Institute? Is it functional?
The ARI was officially opened on July 1, 2002. We have a laboratory
in Philadelphia which is where Kurt Stenn is stationed, our
Chief Scientific Officer. It’s housed in a biotech incubator
space at the University of Pennsylvania. And at the same time
in Atlanta we have a laboratory which is where our bioengineering
group is located.
does what at the two facilities?
group in Philadelphia is looking at the molecular cell biology
aspect and the group in Atlanta is looking at how we take
those cells and put them into the patient's skin in a way
that’s routine and gives predictable results from patient
Bioamide part of the group in Atlanta?
that was formerly Bioamide which was acquired by us and combined
with some additional scientists under Kurt Stenn.
you took over Bioamide they were already working on their
own projects. Have you let them continue working on their
existing projects or have you diverted them to now work on
something that you have envisioned is the right way to go?
would say both. The scope of what they were working on has
definitely been expanded because of the scientists in Philadelphia
and a broadening of the cellular biology knowledge that Kurt
Stenn's group has brought into it, but the basic concept is
still the same.
reason why I am asking is that they have an existing patent
whereby they inject cells under the skin as a progenitor of
a hair follicle, which was very interesting.
they are still working on that and all the intellectual property
they had before they are continuing to work on now.
successful was that research?
you look at publicly presented publications on this technology,
hair cloning, there are only two records of people having
done that with human hair. One was Colin Jahoda who had that
paper published in Nature, and the other one was Tom Barrows
from Bioamide who presented a paper at a bio engineering conference
in Switzerland in 2001. Bioamide did grow hair in one patient
using cultured dermal follicular fibroblasts or dermal papilla
cells. So they are the only ones who have taken human cells,
cultured them, injected them back into a person and have gotten
hair to grow.
this follicular neogenesis, creating brand new follicles from
scratch, or reactivating an existing dormant follicle?
was follicular neogenesis, creating a follicle from scratch.
Now not enough work has been done yet for us to know if this
will always be the case. We don’t know if a surgeon
who places a progenitor of cells near a dormant follicle will
cause it to be reactivated. I would prefer that this be the
case because then we don’t have to worry about direction,
location and naturalness of the hair. So that’s my fantasy
but it looks for now like it will be follicular neogenesis.
to Part 2