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Topic Title: I think we should be making our topicals into creams and NOT ethanol/PG based liquids
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Created On: 07/10/2012 06:21 AM
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 07/10/2012 06:21 AM
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Celco
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I think we would be better off making having our topicals as creams rather than ethanol and PG based liquids.

I think ethanol and PG can potentially irritate the scalp and minimise the benefit we get from topicals.

Does anyone have any thoughts on how to make a non-irritating cream that can be used as vehicle for RU and Minox?

Edit: Just googled Minoxidil cream. It already exists.

-------------------------
1.25mg Fin daily
Minox foam or liquid intermittently
Nizoral shampoo every 2-3 days
----------------
We need something better than Fin approved that targets the scalp only.
We need much better hair growth stimulants.
 07/10/2012 08:52 AM
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Rock'n'Rolla
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Can you provide a legit link to buy Minox cream? Thanks.
 07/10/2012 07:33 PM
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Celco
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Originally posted by: Rock'n'Rolla

Can you provide a legit link to buy Minox cream? Thanks.


http://www.amazon.com/BIANCA-R...l-Cream/dp/B003KX2P7A

The customer review for this don't look good though. Might be better if we could find a way to make it up ourselves with a low irritant cream.

-------------------------
1.25mg Fin daily
Minox foam or liquid intermittently
Nizoral shampoo every 2-3 days
----------------
We need something better than Fin approved that targets the scalp only.
We need much better hair growth stimulants.
 07/11/2012 10:11 AM
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confused
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The alcohol makes massive flakes on my head.like *****ing paint.

I wanted to go directly on ru but the vehicle makes it a problem.I'm now using fin and looking at making my own topical spiro.
 07/11/2012 04:22 PM
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el_duterino
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You can use much less ethanol than 2/3 in order to dissolve RU and replace pg with aloe Vera

Creams won't reach the scalp very well and waste a lot of RU unless you have no hair in which case RU won't help anyway

-------------------------
FIN (1998 to 2004)
DUT (2004-2008)
DUT + Flutamide & Fluridil (2008)
DUT + RU (end 2008)
RU only (dosages 20mg to 400mg/day 2009-2011)
RU+Minox (2011- current)

At present: only RU 20 to 60mg/day (depending on hair length) mixed with Minox 5%
 07/11/2012 05:42 PM
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Celco
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Originally posted by: confused
The alcohol makes massive flakes on my head.like *****ing paint.

I wanted to go directly on ru but the vehicle makes it a problem.I'm now using fin and looking at making my own topical spiro.


Its either the ethanol or the propylene glycol that may be causing the adverse reaction on your scalp.

Given that we now know that pgd2 is upregulated in balding scalp I think avoiding prop glycol and ethanol is a good idea. Both can cause inflammation which may lead to an upregulation of pgd2.

Thats why a non-irritant cream may be better for some if it eliminates or reduces propylene glycol and ethanol on the scalp. Spiro is already available as cream.

-------------------------
1.25mg Fin daily
Minox foam or liquid intermittently
Nizoral shampoo every 2-3 days
----------------
We need something better than Fin approved that targets the scalp only.
We need much better hair growth stimulants.

Edited: 07/11/2012 at 05:52 PM by Celco
 07/11/2012 05:51 PM
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Celco
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Originally posted by: el_duterino
You can use much less ethanol than 2/3 in order to dissolve RU and replace pg with aloe Vera

Creams won't reach the scalp very well and waste a lot of RU unless you have no hair in which case RU won't help anyway


Ive been using spiro cream recently. I find the cream MUCH easier to apply than liquid minox/ru.

The liquid would run down my scalp and forehead and be wasted. With cream you can put small amounts on your fingers and rub it in hard exactly where you want it. Cream is also much easier and better to apply along the hairline and temples.

For short/medium length hair like mine a cream is 10x easier to use than the messy liquid or foam. And with the cream i get none of the inflammation/pain/shedding I got with alcohol/ppg liquid minox or ru.

-------------------------
1.25mg Fin daily
Minox foam or liquid intermittently
Nizoral shampoo every 2-3 days
----------------
We need something better than Fin approved that targets the scalp only.
We need much better hair growth stimulants.
 07/11/2012 10:07 PM
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el_duterino
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I used RU with aloe Vera gel, very soothing on the scalp and dries fast too, and just a little bit of ethanol to dissolve RU, perhaps 0.5 ml, which not enough to cause any skin issues even for the most sensitive girl out there.

Topical spiro is significantly weaker than RU and not worth the effort unless your hair loss is very mild.

-------------------------
FIN (1998 to 2004)
DUT (2004-2008)
DUT + Flutamide & Fluridil (2008)
DUT + RU (end 2008)
RU only (dosages 20mg to 400mg/day 2009-2011)
RU+Minox (2011- current)

At present: only RU 20 to 60mg/day (depending on hair length) mixed with Minox 5%
 07/11/2012 10:32 PM
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Rock'n'Rolla
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So you have replaced PG with aloe now?
 07/12/2012 02:11 AM
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Rock'n'Rolla
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El_dut, what % RU58841 solution do you make? 5% or 2%?
 07/12/2012 11:11 AM
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confused
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Originally posted by: el_duterino

You can use much less ethanol than 2/3 in order to dissolve RU and replace pg with aloe Vera



Creams won't reach the scalp very well and waste a lot of RU unless you have no hair in which case RU won't help anyway



Excellent.will be giving this a go...
 07/12/2012 06:38 PM
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Celco
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Originally posted by: el_duterino
I used RU with aloe Vera gel, very soothing on the scalp and dries fast too, and just a little bit of ethanol to dissolve RU, perhaps 0.5 ml, which not enough to cause any skin issues even for the most sensitive girl out there.


The issue here isn't about being a sensitive girl. It's about ethanol and PPG being linked to possible skin inflammation and allergic reactions.

Given that we know that inflammatory infiltrates exist around balding follicles (shown in scientific studies) and one of those factors, PGD2, has been clearly shown to stop hair growing, I think it's a clever move to minimise exposure to ethanol and PPG as much as possible. That is all I am saying.

I will try the aloe.

-------------------------
1.25mg Fin daily
Minox foam or liquid intermittently
Nizoral shampoo every 2-3 days
----------------
We need something better than Fin approved that targets the scalp only.
We need much better hair growth stimulants.
 07/12/2012 09:07 PM
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Swoosh
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What kind of aloe is best? Most of the products on the market have other ingredients like gums or preservatives.

el_dut, do you still use aloe for your RU?
 07/12/2012 10:54 PM
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jonson123
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Originally posted by: Celco

Originally posted by: el_duterino

I used RU with aloe Vera gel, very soothing on the scalp and dries fast too, and just a little bit of ethanol to dissolve RU, perhaps 0.5 ml, which not enough to cause any skin issues even for the most sensitive girl out there.





The issue here isn't about being a sensitive girl. It's about ethanol and PPG being linked to possible skin inflammation and allergic reactions.



Given that we know that inflammatory infiltrates exist around balding follicles (shown in scientific studies) and one of those factors, PGD2, has been clearly shown to stop hair growing, I think it's a clever move to minimise exposure to ethanol and PPG as much as possible. That is all I am saying.



I will try the aloe.
 07/12/2012 11:34 PM
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el_duterino
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I don't use aloe anymore because I like to have thin liquids which dry fast and ethanol/pg works fine for me , i don't have a sensitive scalp or other skin issues.I also use Minox liquid and it's basically the same type of vehicle.

the Aloe I used was more like a gel.

Agin, Millions of men have been using Minox in alcohol / PG for decades with no issues on hair or scalp so there is no need to become paranoiac now, but if you really need to use other vehicles then Aloe is a good and cheap option, other experiments might work too however oils such as Emu do not mix with ethanol and you need at least a small amount of ethanol just to dissolve RU

-------------------------
FIN (1998 to 2004)
DUT (2004-2008)
DUT + Flutamide & Fluridil (2008)
DUT + RU (end 2008)
RU only (dosages 20mg to 400mg/day 2009-2011)
RU+Minox (2011- current)

At present: only RU 20 to 60mg/day (depending on hair length) mixed with Minox 5%
 07/13/2012 03:26 AM
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Celco
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Originally posted by: el_duterino
Agin, Millions of men have been using Minox in alcohol / PG for decades with no issues on hair or scalp so there is no need to become paranoiac now, but if you really need to use other vehicles then Aloe is a good and cheap option, other experiments might work too however oils such as Emu do not mix with ethanol and you need at least a small amount of ethanol just to dissolve RU


I don't think I'm becoming overly paranoid, just using what we are learning about hairloss to fine tune treatments.

Here's something to look at.

http://www.dermlasersurgery.co..._dermatitis.pdf


Ethanol, PPG - these are not great things to be putting on a balding scalp twice daily if you can avoid it. Although PPG may be more of a problem than ethanol.

-------------------------
1.25mg Fin daily
Minox foam or liquid intermittently
Nizoral shampoo every 2-3 days
----------------
We need something better than Fin approved that targets the scalp only.
We need much better hair growth stimulants.
 07/16/2012 01:45 AM
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pikaczu
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Originally posted by: el_duterino

I don't use aloe anymore because I like to have thin liquids which dry fast and ethanol/pg works fine for me , i don't have a sensitive scalp or other skin issues.I also use Minox liquid and it's basically the same type of vehicle.



the Aloe I used was more like a gel.



Agin, Millions of men have been using Minox in alcohol / PG for decades with no issues on hair or scalp so there is no need to become paranoiac now, but if you really need to use other vehicles then Aloe is a good and cheap option, other experiments might work too however oils such as Emu do not mix with ethanol and you need at least a small amount of ethanol just to dissolve RU


You can mix ethanol with Emu oil if the amount of eth in Emu is less than 5%.
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