http://www.intercytex.com/icx/products/aesthetic/icxtrc/

Have a look a the link above.

Phase 1 trials were a success - the article says that 5 out of the 7 volunteers exhibited hair growth, remember that phase 1 trials were to only measure safety and NOT hair growth and only a small sample was used. The phase 2 trials which will be carried out this year will look at safety issues and hair growth in a larger number of people.

We could have a viable treatment by 2008 if everything goes according to plan.

Maxwell.

How legit is this?
Regrow hair is such a vague claim. I have to be skeptical with these new treatments but I do hope that they work

You have to keep in mind that the "hair growth" that they got was not the regrowth we normally think of. What we consider growth is using treatments to turn vellus hairs/no hairs back into terminal hairs (which give cosmetic effect). In this case, these scientists are making hair out of nothing, basically.

So when they say that 5 out of 7 patients experienced hair growth, they are not talking about revival of old hairs, they're talking about the creation of new ones. Pretty exciting if you ask me.

That's right. The treatment Intercytex is working on doesn't aim to stimulate dead or dormant follicles into growing, it causes new hair follicles to form and grow, replacing the old dead ones. The dermal papillae cells they inject act sort of like a "seed" from which a hair grows. I think the idea is that a new hair (or even several hairs, a FU) will grow at each injection. Obviously they are investigating the degree of success in clinical trials. There is some speculation though, that the new growing follicles give off chemical signals to other surrounding dormant follicles, causing them to come back to life.

Who knows? It's definitely one of the more exciting treatments to come along, because its totally unlike anything available today.

That is promising. Even if HM were to come out I would think extreme density would be an issue, I'm not sure what densities of non-balding men are, by my hair was thick like Patrick Dempsey, I dont see getting that from traditional methods. Lets keep our fingers crossed and hope this works and is fast and affordable.

This sounds awesome since im just thining!!! I can't wait for 2007 it seems, forget the HT im going for this sucker!

so if I understand it all well, intercytex is only transplanting the dermal papilla cells. If that's really the case, this is not good news at all. Dermal papilla cells are the cells responsible for hair growth, but they need signalling from the hair stem cells. The hair stem cells stop signalling the DP-cells when DHT attaches to its receptors.

So if you bring in new dermal papilla cells, a new hair will be formed, but the hair will stop growing immediately after the first cyclus due to non-functioning stem cells.

Edited: 05/11/2006 at 06:53 AM by tupperware

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Originally posted by: tupperware
so if I understand it all well, intercytex is only transplanting the dermal papilla cells. If that's really the case, this is not good news at all. Dermal papilla cells are the cells responsible for hair growth, but they need signalling from the hair stem cells. The hair stem cells stop signalling the DP-cells when DHT attaches to its receptors.

So if you bring in new dermal papilla cells, a new hair will be formed, but the hair will stop growing immediately after the first cyclus due to non-functioning stem cells.

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With All due respect tupperware,what makes you think these scientists have already thought about this before spending millions on taking this treament in to the fda stages, please!!!!!.
The other thing is that these dp cells are taken from the back of the head where dht cells are resistant to the effects of dht this is how i understand it, but like always i would stand to be corrected,but to me this is obvious that this is the closest will will get in our lifetime to a cure/treatment!!

Oh the other thing i forgot to mention is that the greatest worry is that after cycle meaning anagen,telgen catagen that the hair wont reproduce a new follicle!!!!!! this could take up to 3 years to know.

Well I suppose you could solve this problem much faster by transplanting eyebrow or chest hair. Those cycle much faster.

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Originally posted by: LMH
<blockquote>Quote

With All due respect tupperware,what makes you think these scientists have already thought about this before spending millions on taking this treament in to the fda stages, please!!!!!.
The other thing is that these dp cells are taken from the back of the head where dht cells are resistant to the effects of dht this is how i understand it, but like always i would stand to be corrected,but to me this is obvious that this is the closest will will get in our lifetime to a cure/treatment!!

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Maybe that's exactly what they want, a cure that only lasts 1 cycle (= 5 years), so the costumers keep coming back.

And by the way, it doesn't matter if you get the DP-cells from the back of your head, it's the STEM CELLS that have the DHT-sensitive receptors.

But I don't know exactly how this technique works, I'm just thinking out loud and share you my question marks.

Yeah, fair comment !!!

Lets see what these trials show up in the next few years then maybe, we can all have a better judge.
It frustrating to know that we are on the brink on of a radical change in the way we treat hair loss and then in the other hand, there so much more that we dont know.It seems for every one thing we discover it brings along another 10 things we dont know!

All I know is I would have been more than happy to be 1 of their guinea pigs in this trial.

It sounds very interesting if it works!

KJ

what's involved in a regular old transplant of follicular units from the back? I'm asking because i don't know. if those don't involve stem cells and only dp cells then tupperwares reasoning is faulty.

Nearly 1-1/2 years after the original post touting Intercytex's Phase I result they still haven't started Phase II trials yet.

I think they may be finding difficulties in recruiting suitable candidates., ie men who do not use minox, finast, nizoral etc etc and who have not already had an HT!!

Also in the UK a number of people have been killed/maimed by a recent drug-testing trial that went horrendously wrong....this could be putting applicants off.

I personally believe that it's gonna start this month.

Guys phase 2 has already started and will complete in april 2007, i contacted them to be a guinea pig, but they said they only wanted men from manchester area and not birmingham where i am from;o(

Only 6 months????
Isnt that a little too soon?

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First transplant with karamikian 6/05, less than 1000 to my hairline, result was mediocre at best.
2nd HT, this time with DR Feller 2/08, 3000+ to my front third.
Came out well, however due to thin hair characteristics, I need more for a fuller look.

3rd HT with Dr Feller 9/09. Roughly 1000 into my crown, and roughly 1500 into the thin front 1/3 portions as well as the hair behind the 2nd HT that receded.