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Topic Title: Topical Vasodilators?
Topic Summary: Any thoughts...
Created On: 04/25/2010 07:19 AM
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 04/25/2010 07:19 AM
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Celco
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Does anyone know of any potentially useful topical vasodilators that may be used on the scalp?

The theory is that improving blood circulation in the scalp may help slow the miniaturisation process.

I have a product that claims to be a vasodilator for the scalp. It's a topical. You apply it to the scalp, massage for 5 mintues and leave it in.

The ingredients list for it are:

-Filtered water

-Ethanol

-Propylene Glycol

-Yeast Extract

-Polysorbate 20

-Menthol

-Biotin

-Insositol

-Disodium EDTA

-Methyl & Propyl Hydroxybenzoate

-Phenoxyethanol

- Cl 19140

Would any of these ingredients be of any use or is the product a scam?

Are there any other products that could be used as a topical vasodilator for the scalp?

 



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1.25mg Fin daily
Minox foam or liquid intermittently
Nizoral shampoo every 2-3 days
----------------
We need something better than Fin approved that targets the scalp only.
We need much better hair growth stimulants.
 04/25/2010 07:52 AM
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LosingBattle
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isn't minoxidil a vasodilator?
 04/25/2010 08:05 AM
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ItzMeCorey
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Originally posted by: LosingBattle isn't minoxidil a vasodilator?
ya

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Supplement: R-ALA, Frm Cod Liver, Encapsulated Probiotics, etc...
 04/25/2010 08:56 AM
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Mopless
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Originally posted by: LosingBattle

isn't minoxidil a vasodilator?


Far as I know, NO. It was thought to be for awhile, but later found out it was not the case. The current theory is it has something to do with opening potassium channels in the hair follicle. Or something like that.

Anyone please step it to correct me or if you have something to add.



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Regime - Fin 0.25mg eod or whenever I remember - Miconozole cream daily - Keto Shampoo daily - 1.5mm Needling when I feel like it.
 04/25/2010 11:20 AM
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JohnDavid45
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Caffeine & Vit-C are both aggressive dilators, although Vit-C has a fairly short half-life in the blood (not sure about topical application). Bear in mind that our scalps are already highly saturated with blood. Even in smokers, there is an abundance of blood-flow to the scalp; at least, going by my dermatologist.



-------------------------
-5% Spiro Cream (daily)
-Prox-N (daily)
-5% Minox with phen (daily)
-NANO Shampoo (3/weekly)
-Nizoral (3/weekly)
-Ginger Scalp Care Shampoo [Piroctone Olamine] (1/weekly)
 04/25/2010 12:51 PM
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Iggy Pop
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does ur derm know ur using ru58841 JohnDavid?

 

 04/25/2010 01:27 PM
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JohnDavid45
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No. I'm going to tell him during my next visit, which isn't until August.

-------------------------
-5% Spiro Cream (daily)
-Prox-N (daily)
-5% Minox with phen (daily)
-NANO Shampoo (3/weekly)
-Nizoral (3/weekly)
-Ginger Scalp Care Shampoo [Piroctone Olamine] (1/weekly)
 04/25/2010 02:01 PM
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cliquesh
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Originally posted by: Mopless
Originally posted by: LosingBattle isn't minoxidil a vasodilator?
Far as I know, NO. It was thought to be for awhile, but later found out it was not the case. The current theory is it has something to do with opening potassium channels in the hair follicle. Or something like that. Anyone please step it to correct me or if you have something to add.

Minoxidil is a vasodilator. It works, as you said, by opening potassium channels, which causes smooth muscle cells to become hyperpolarized, which makes it more difficult for them to contract. So, if you take a lot of minoxidil, your blood pressure will decrease, and your body will respond by increasing your heart rate. It is unclear why minoxidil regrows hair.

Adenosine, which is used for AV node tachycardias, also opens potassium channels. I wonder if adenosine has ever been studied as a hair loss drug.

Edit: I just looked it up, and apparently adenosine is useful:

"It has been shown that, in Japanese men, adenosine improves androgenetic alopecia due to the thickening of thin hair due to hair follicle miniaturization."

Source:http://www.ncbi.nlm.nih.gov/pubmed/19239555

Diazoxide is another hypertension medication that opens potassium channels, but Diazoxide is pretty strong. Much stronger than minoxidil in regards to vasodilation.



Edited: 04/25/2010 at 02:24 PM by cliquesh
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