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Topic Title: Using carrier oils (with ethanol, etc.) to deliver topicals?
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Created On: 01/10/2017 02:22 PM
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 01/10/2017 02:22 PM
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Posts: 1662
Joined: 09/17/2002

Heyas gents, I'm back after a long time off.

Question. I've always used ethanol/PPG (or glycine) mixes (sometimes thowing in DMSO or other penetration enhancers) to try and deliver topicals like fin, flutamide, etc.

However, these have always dried my scalp and caused hairs to fall out, with skin often flaking off.

Recently, however, I tried using mixes of 50% carrier oils (sometimes including a bit of essential oils) and 50% the ethanol, etc. drug mix. I must say, my hairs falling out has dropped to almost nothing. I can't seem to get this result by applying the two separately, even in close proximity - the ethanol mix seems to do its drying, etc. damage very quick.

Any reason not to just combine them as I've started doing? I don't think any of the drugs should come out of the solution because there is still the same amount of ethanol etc. in there before. I've stuck my finger to the bottom of the mix to see whether I ever feel anything grandular, like a drug came out of the solution, but never had.

Any reason not to keep doing this? Obviously I'll have to do it twice as much to get the same effective dosage of the underlying topical drug.

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