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Topic Title: The cure for hairloss!!!!
Topic Summary: Histogen phase 2 update at 3 months
Created On: 05/15/2012 01:44 PM
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 05/15/2012 08:55 PM
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Erick.
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Even if it's hideously expensive I'd choose this over a hair transplant any day...

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24/M
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 05/15/2012 08:56 PM
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vintervagen
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I'm happy and hopeful!

If Histogen does succeed, all I need is to win a jackpot in a lottery or receive a donation from Warren Buffett and I'm good to go. I can barely afford Propecia. It's going to be a bummer being a baldie with a treatment out there you can not afford.
 05/15/2012 08:57 PM
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TwentySomething
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There will always be the bitter stragglers that rain on parades, but this is great news, thanks for posting. I agree with Calvin - I would ABSOLUTELY shell out $50k for a permanent fix that would save me the hassles of trying numerous treatments, topicals etc. The hassle saved alone would be incredible, not to mention the effectiveness.

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Regimen [Started Oct 1, 2012]:
- 1x / day 1.5ml 5-7.5% RU in KB solution
 05/15/2012 09:55 PM
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caco
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 05/15/2012 10:07 PM
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Loki
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I'm sure every man, woman and child who is losing their would be willing to pay $100,000 to have their hair back, that doesn't mean that every man, woman and child can in reality do that, it amazes that people don't seem to get that, the world is currently going through the worst economic period since the great depression, most people I know are feeling the squeeze, middle class Americans must be doing much better than I thought if they have a spare $100,000 to fall back on.
 05/16/2012 12:12 AM
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KO
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Forget about prices. Has histogen actually shown data showing growth for the experimental group as a whole? Definitely interested in seeing that info.
 05/16/2012 12:15 AM
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mintyfresh
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Ok maybe I spoke too soon (maybe), these results if true do seem interesting, however something about those photographs bugs me,

1. take a look at the first baseline picture of the close up under the microscope S1016
why does it look like there are many already terminal hairs that seem to be shaved down to stubble? zoom right in, it's so obvious,

2. in the pictures of the woman's hair line, why is it that in the baseline pictures her hair is pulled tight back from the forehead,
and in the 12 weeks pictures the hair is allowed to drape forward over the balding areas, to such a degree that we can't see exactly which areas of the scalp the hair is actually growing from,
zoom right in and you'll see exactly what I'm talking about


this sort of thing bugs the crap out of me
 05/16/2012 12:43 AM
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Save the Forest
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So it looks to me like this Phase II will be done in June 2013, then they have to recruit and run a Phase III. I wonder how long we are looking at, even in Asia.

http://clinicaltrials.gov/ct2/...?term=histogen&rank=1

Here is an interview where she talks about an Asian release timelime, but her possible 2013 date was predicated on this Phase I/II trial starting in 2010 and it started in Dec. 2011.

http://www.thebaldtruth.com/ar...80%9D-as-soon-as-2013/
 05/16/2012 01:02 AM
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dogs3
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Originally posted by: mintyfresh

Ok maybe I spoke too soon (maybe), these results if true do seem interesting, however something about those photographs bugs me,



1. take a look at the first baseline picture of the close up under the microscope S1016

why does it look like there are many already terminal hairs that seem to be shaved down to stubble? zoom right in, it's so obvious,



2. in the pictures of the woman's hair line, why is it that in the baseline pictures her hair is pulled tight back from the forehead,

and in the 12 weeks pictures the hair is allowed to drape forward over the balding areas, to such a degree that we can't see exactly which areas of the scalp the hair is actually growing from,

zoom right in and you'll see exactly what I'm talking about





this sort of thing bugs the crap out of me


I dont know man, the pictures of that woman's temples look pretty legit to me. But I certainly would like to see some more photos, and especially of men, before proclaiming this to be the cure.
 05/16/2012 01:02 AM
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richhairman
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I smell a scam. This will go no where.
 05/16/2012 01:44 AM
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PrasadKannan
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Start saving lads!!!

I hope this forum and all the dogma associated with hairloss vanishes in a couple of years

Time to stay possitive

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1 mg Finastride
1 Multi Vitamin
100 mg Coq 10
100 mg L-Carnitine
100 mg Cod Liver Oil
30 mg Tocotrienol
50 mg Garlic Pills
100 mg Flax Seed Oil
5 mg Biotin
100 mg Acai Berry
 05/16/2012 01:53 AM
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richhairman
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keep dreaming.
 05/16/2012 01:53 AM
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PrasadKannan
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Enrollment of 56 patients with male pattern hair loss in the Phase I/II clinical trial of HSC has been completed, and the trial is ongoing. Dr. Gail Naughton, Histogen CEO and Chairman of the Board, presented the 12 week primary safety and efficacy data at the Society for Investigative Dermatology (SID) Annual Meeting on May 11, 2012.

Sounds like most of the patients were men (http://www.histogen.com/applications/hsc.htm)

-------------------------
1 mg Finastride
1 Multi Vitamin
100 mg Coq 10
100 mg L-Carnitine
100 mg Cod Liver Oil
30 mg Tocotrienol
50 mg Garlic Pills
100 mg Flax Seed Oil
5 mg Biotin
100 mg Acai Berry
 05/16/2012 02:10 AM
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Celco
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.

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1.25mg Fin daily
Minox foam or liquid intermittently
Nizoral shampoo every 2-3 days
----------------
We need something better than Fin approved that targets the scalp only.
We need much better hair growth stimulants.

Edited: 05/16/2012 at 02:18 AM by Celco
 05/16/2012 02:31 AM
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DarkMatter
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*does moonwalk across the room*
 05/16/2012 03:31 AM
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PrasadKannan
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My girl wants to party all the time,party all the time,party all the time.....


It's time to party people!!!

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1 mg Finastride
1 Multi Vitamin
100 mg Coq 10
100 mg L-Carnitine
100 mg Cod Liver Oil
30 mg Tocotrienol
50 mg Garlic Pills
100 mg Flax Seed Oil
5 mg Biotin
100 mg Acai Berry
 05/16/2012 06:37 AM
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Kirby
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I'm thrilled by this progress after the Replifail debacle. I know it's not all "in the bag" yet, but this treatment would be ideal for diffuse-balders like myself.
 05/16/2012 07:08 AM
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padstar
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Impressive! Will the new hairs still be prone to miniturisation, and will fin/dut still be needed?
 05/16/2012 10:11 AM
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PrasadKannan
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I found this Q&A on another forum, it might awsner a few questions you guys have. Turns out HSC will work on all forms of hair loss, and transplanted areas.
_________________


Dr Craig L. Ziering (Histogen's principal clinical investigator) answered to some questions from users on the ************* forum back in February:


Q. Do you think a person who's approaching a Norwood 5 or 6 can be helped with Histogen?

A. It has the potential to treat all stages of hairloss.
http://www.*************.com/showpost.p ... stcount=25


Q. Will having a hair transplant now will interfere with having Histogen injections in the future?

A. No , having a transplant now will not prevent you from receiving HSC injections in the future. The great thing is that HSC works on the recipient area and has nothing to do with the donor at this time . This should give new hope to all those that have poor or no donor hair available.


Q. Aside from Singapore I haven`t heard of any other countries in Asia taking part in the trials. Which, if any, other countries are going to take part in the trials? Thanks.

A. Right now Singapore but possibly Korea


Q. I got an email from gail naugton last month saying "We are starting phase 1/2 in Singapore before the end of May and hope to have phase 3 pan-Asian data by Sept 2012 for an NDA submission and 2013 approval. (hopefull Q2 2013)."

Is it possible that the NDA submissions could be shortened? Does it have to be 6-12 months long?

Is it possible to lobby the Singapore Health Authority to shorten it?

A. Sorry , but I dont see this time frame being shortened.

Q. Are the new hairs from the HSC injections colored hair, for a person with greying hair?
For example if a person has white hair (ie anderson cooper) will the new grown hairs from HSC injections be white or black?

A. The hair would likely take on its original darker color.


Q. 1. It has not become clear to me what exactly are the results 2 years after one single injection. I can see pictures on the Histogen website which show the hair growth after 12 weeks, 5 month and 12 month. As i can see in the statistics below the the pictures, after 12 month there is still new and thicker hair growing. Now after 2 years, is there still an increase in numbers of hair and hair thickness? I mean compared to the 1 year update, are there now more and thicker Hairs? Or were the 1 year results just lasting for one more year?

2. Will there be an update on the Histogen website which shows macrophotos and statistics regarding the 2 year results?

A. The Histogen study was originally a safety study with 12 mos follow up, with efficacy as a secondary endpoint. The Company was able to modify the clinical protocol to add a two year safety endpoint but couldn't perform the full efficacy study. Photos were taken of the treatment site which indicate persistence of hair at the treatment site but an accurate hair number and thickness assessment can not be done. The scientists at Histogen believe that the new hairs seen at 1 year are a result of stimulating stem cells in the scalp and in existing normal and miniaturizing follicles to grow new hairs. There is no reason to believe that additional hairs would be stimulated after one year with only one injection at baseline. That being said, the fact that new hairs continue to grow over the one year period is quite remarkable and unprecedented in the hair growth field.

Histogen is performing exploratory case studies in Asia where patients are receiving 50+ injections at base line to assess hair growth over time. The Company hopes to have initial results from the first case studies in the next four weeks and plans on sharing those with the hair transplant community.

-------------------------
1 mg Finastride
1 Multi Vitamin
100 mg Coq 10
100 mg L-Carnitine
100 mg Cod Liver Oil
30 mg Tocotrienol
50 mg Garlic Pills
100 mg Flax Seed Oil
5 mg Biotin
100 mg Acai Berry
 05/16/2012 10:22 AM
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2020_2
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A. The hair would likely take on its original darker color.


huh?? It also fixes grey hair??
Hair Loss Help » Hair Loss Open Topic » The cure for hairloss!!!!

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