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Topic Title: Strongest/Best DHT Blocker or Inhibitor??
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Created On: 09/06/2004 05:19 AM
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 09/06/2004 05:19 AM
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killern
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Hello
What do you mean is the best or strongest natural DHT Blocker/Inhibitor. No synthetics please! You can also write down more than one DHt Blocker if you mean a Complex is the best but also tell me what is the strongest taken alone.

greets....
 09/06/2004 10:55 PM
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Socks
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Nothing that is taken internally, other then Finasteride or Dutasteride, has been shown effectively reduce DHT serum levels in the body. As far as externals, nothing has been shown to effectively reduce DHT levels in-vivo in independent clinical trials that could stand up to medical scrutiny.

Your **BEST bet** is to take 1mg of Finasteride daily and use Nizoral 2% shampoo every other day. This is a PROVEN routine that works.
 10/05/2004 10:49 PM
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Mr. Harry
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There's definitely some effect on dht by saw palmetto. There's even at least one positive pilot study with saw palmetto and androgenetic alopecia. But you're correct that it was very hard to find articles that specifically measured dht reduction by saw palmetto. Here's one.





Urology. 2001 May;57(5):999-1005. Related Articles, Links


Tissue effects of saw palmetto and finasteride: use of biopsy cores for in situ quantification of prostatic androgens.

Marks LS, Hess DL, Dorey FJ, Luz Macairan M, Cruz Santos PB, Tyler VE.

Urological Sciences Research Foundation, Culver City, California, USA.

OBJECTIVES: To determine the effects of a saw palmetto herbal blend (SPHB) compared with finasteride on prostatic tissue androgen levels and to evaluate needle biopsies as a source of tissue for such determinations. METHODS: Prostate levels of testosterone and dihydrotestosterone (DHT) were measured on 5 to 10-mg biopsy specimens (18-gauge needle cores) in three groups of men with symptomatic benign prostatic hyperplasia: 15 men receiving chronic finasteride therapy versus 7 untreated controls; 4 men undergoing prostate adenomectomy to determine sampling variability (10 specimens each); and 40 men participating in a 6-month randomized trial of SPHB versus placebo, before and after treatment. RESULTS: Prostatic tissue DHT levels were found to be several times higher than the levels of testosterone (5.01 versus 1.51 ng/g), that ratio becoming reversed (1.05 versus 3.63 ng/g) with chronic finasteride therapy. The finasteride effect was statistically significant for both androgens (P <0.01), and little overlap of individual values between finasteride-treated and control patients was seen. In the randomized trial, tissue DHT levels were reduced by 32% from 6.49 to 4.40 ng/g in the SPHB group (P <0.005), with no significant change in the placebo group. CONCLUSIONS: For control versus finasteride-treated men, the tissue androgen values obtained with needle biopsy specimens were similar-both for absolute values and the percentage of change-to those previously reported using surgically excised volumes of prostatic tissue. The quantification of prostatic androgens by assay of needle biopsies is thus feasible and offers the possibility of serial studies in individual patients. The SPHB-induced suppression of prostatic DHT levels, modest but significant in a randomized trial, lends an element of support to the hypothesis that inhibition of the enzyme 5-alpha reductase is a mechanism of action of this substance.

Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 11337315 [PubMed - indexed for MEDLINE]
 10/18/2004 10:18 PM
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Old Baldy
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Castration! Just kidding guys, I've had a few shots of whiskey tonight.
 11/01/2004 09:51 PM
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aussiegirl
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Revivogen. Go to www.revivogen.com to check it out.
 11/07/2004 08:31 AM
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GoSox
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mr harry.. I just added sp to my routine... how much should I be taking a day though?
 12/01/2004 06:21 PM
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Danderlin
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Quote

Originally posted by: Socks
Nothing that is taken internally, other then Finasteride or Dutasteride, has been shown effectively reduce DHT serum levels in the body. As far as externals, nothing has been shown to effectively reduce DHT levels in-vivo in independent clinical trials that could stand up to medical scrutiny.

Your <b>**BEST bet**</b> is to take 1mg of Finasteride daily and use Nizoral 2% shampoo every other day. This is a PROVEN routine that works.


Not true.

This Finast/Nizoral routine does not work. I've been doing it for a couple years now with no results. I started early before things were bad, I did everything right and I haven't even maintained, it gets thinner and worse everyday with continual fall out. This works for SOME not all.
 12/03/2004 06:23 AM
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hair_tomorrow
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yea - as far as the natural route goes - it looks like zix and revivogen.

I guess spironolactone isn't a natural product - but using both topical spiro and revivogen supposedley blocks all bad dht (I'll let you know this summer).

-------------------------
hair_tomorrow@usa.com ~ NW5A ~ Dut: 2x weekly; Proscar: 1 mg 4x weekly ~ Minomuck ~ SuperZix II ~ Copper Peptides ~ Shampoos: rotate Dr. Lee's Regrowth, "Thicker Fuller Hair" w/ caffeine, Biotin w/ TTO ~ Emu & Essential Oils ~ Varied OTC Supplements
 12/04/2004 07:48 AM
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hairmo
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Quote

Originally posted by: Socks
Your <b>**BEST bet**</b> is to take 1mg of Finasteride daily and use Nizoral 2% shampoo every other day. This is a PROVEN routine that works.


can somebody please post the clinical study of using 1 mg fin with nizoral 2% every other day? thanks

 12/18/2004 02:43 PM
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hairmo
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its the bump
 12/23/2004 09:31 AM
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durango
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GoSex: For SAW Palmetto, I would buy a vitamin that contains 160mg (85-95% free fatty acides, standardized) and take it TWICE a day. For a total gain of 320mg daily.
 12/23/2004 08:37 PM
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eurotrash
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Here's my opinion on the subject. It might be just one voice out of many but I've tried several options and I've actually gotten results that I can live with now so I'm happy to share if it might help someone. I don't know who came up with the Finasteride/Nizoral combo but here's my take on it: Nizoral is not a mild shampoo. I've used it when I had REALLY bad dandruff in winter and let me tell you, it isn't mild for your hair. You should never use that stuff on your hair even if it's every other day, especially if your hair is falling out. Why would you want to damage the hair you still have??! As for Finasteride, my experience is that it works FOR WHAT IT'S SUPPOSED TO DO. I started losing my hair at 18. I'm 21 now. I've been taking Propecia (Finasteride) for about 2 years and I noticed that when I brush my hair daily, I find on average 10 to 15 hairs in my brush now. Before, I used to find up to 50 a day. Propecia is good if you're young and you still have hair and you want to keep it. That's the main purpose of the drug. I'm not sure if it regrows hair but it does a fine job at keeping the hair on your head from falling. If you want more hair, there are very few methods that actually work. I personally think hair transplants are definetly worth the money. As for day to day haircare. Use a mild shampoo if you wash your hair daily like I do and a light conditioner after you shampoo to keep your hair strong and prevent breakage. From my experience, you get what you pay for and if you want nice hair, you gotta be willing to spend $$$ on it.

Edited: 12/23/2004 at 08:54 PM by eurotrash
 12/26/2004 09:59 PM
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Socks
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Quote

Originally posted by: Danderlin

Not true.

This Finast/Nizoral routine does not work. I've been doing it for a couple years now with no results. I started early before things were bad, I did everything right and I haven't even maintained, it gets thinner and worse everyday with continual fall out. This works for SOME not all


Danderlin,

I know Finasteride and Dutasteride didnt work for you bud and I'm very sadden to hear that I do wish you the best of luck in finding some routine that will work for you.


Having said that, Finasteride works for most men but not all. Saying it works for some but not all is just not accurate as it may lead one to believe that Finasteride only works for a "lucky few" rather "working for all but an unlucky few".

Edited: 12/26/2004 at 10:12 PM by Socks
 12/26/2004 10:10 PM
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Socks
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Quote

Originally posted by: hairmo
can somebody please post the clinical study of using 1 mg fin with nizoral 2% every other day? thanks


To the best of my knowledge there has been no official study done with Finasteride and Nizoral 2% in tandem. The reason it is recommend to use both Finasteride and Nizoral in tandem is because Finasteride is FDA proven to inhibit DHT production and Nizoral has had studies on it show that its active ingredient Ketoconazole has had an effect in disrupting androgen and thickening hair over 6 months.

Quote

Originally posted by: Eurotrash
Nizoral is not a mild shampoo. I've used it when I had REALLY bad dandruff in winter and let me tell you, it isn't mild for your hair. You should never use that stuff on your hair even if it's every other day, especially if your hair is falling out. Why would you want to damage the hair you still have??!


Like any chemical, some men may have a negative response to Nizoral and this should either use it less or not at all. Having said that, here is some reading to do in regard to why you would want to use Nizoral if you are losing hair:

HLT Newsletter on Nizoral (2 pages)

HLT PDF study

PubMed medical abstract
 12/28/2004 05:52 PM
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HairHope
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Great stuff Socks! Thanks a bunch.
 12/30/2004 11:28 AM
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eurotrash
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Quote

Like any chemical, some men may have a negative response to Nizoral and this should either use it less or not at all. Having said that, here is some reading to do in regard to why you would want to use Nizoral if you are losing hair


If anyone sees results while using Nizoral then that's absolutely great. When I used it, I hated the way my hair was afterwards. I have really fine hair naturally like my mom and Nizoral stripped my hair and scalp completely and left it coarse and breaking. Also, it increased shedding for me coz I would find way more hairs in my brush or when I would run my hands through my hair after it dried completely. And yes I used it for a a few months not just a couple of weeks. Honestly, I don't believe any shampoo will make you regain your hair or stop hair loss or whatever. The best it can do is make the hair you still have look great. Changing shampoos regularly is recommended because your hair adapts to the chemicals. I use Rene Furterer Volume shampoo and conditioner. It's called Fioravanti. It's not a hair loss shampoo but it makes your hair look f***ing amazing. It's expensive so I alternate it with a Clinique shampoo. Neutrogena t gel is good also for getting rid of dandruff.
 12/31/2004 07:05 PM
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LosingItQuickly
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I have personal experience with a decrease in serum DHT with Saw Palmetto. After taking it for a month, my serum DHT dropped from 270 to 120. I know it is still high, but I am happy with the the improvement.

This is in no way to say that this would work for everybody, but I want to stay natural and am pleased with the results thus far.
 01/01/2005 11:16 PM
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durango
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Quote

Originally posted by: LosingItQuickly
I have personal experience with a decrease in serum DHT with Saw Palmetto. After taking it for a month, my serum DHT dropped from 270 to 120. I know it is still high, but I am happy with the the improvement.

This is in no way to say that this would work for everybody, but I want to stay natural and am pleased with the results thus far.


Tell me what kind of SP did you use: Was it extract or whole herb? How much mg/daily? Did it have stinging nettle & Pygeum with it, or just SP?
Thanks
 01/17/2005 11:52 AM
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Old Baldy
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Euro: Place a dab of emu oil in your palm than add a dime size portion of Nizoral to your palm. Then let that mixture soak into your scalp for 5 minutes. Leaves the hair soft. (Heard this tip from a veteran poster a while ago and it works great.)
 01/24/2005 05:13 PM
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durango
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Quote

Originally posted by: LosingItQuickly
I have personal experience with a decrease in serum DHT with Saw Palmetto. After taking it for a month, my serum DHT dropped from 270 to 120. I know it is still high, but I am happy with the the improvement.

This is in no way to say that this would work for everybody, but I want to stay natural and am pleased with the results thus far.




Ok, it decreased your serum DHT levels. But, has it slowed/halted your hairloss?
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